Science

Contact lenses

Can baseline axial length measurements be predictive of OrthoK efficacy?

This retrospective study assessed the relationship between baseline axial length and subsequent elongation for myopes wearing orthokeratology lenses. The results showed axial elongation was slower over two years for younger children with longer baseline axial lengths. This may help in approaches to optimizing myopia control.

Johnson & Johnson Vision myopia research showcased at ARVO 2023

Johnson & Johnson Vision’s intent to lead with science was on full show at the recent ARVO at New Orleans. We look at 5 abstracts they presented, providing you summaries and the abstracts on topics such as efficacy in myopia control, myopia calculators and subjective vision outcomes for children and teens in soft contact lens designs for myopia.

How satisfied are children wearing full-time daily disposable soft contact lenses?

Data from up to six years of wear in the landmark MiSight® 1 day clinical trial has shown similar outcomes for comfort, vision, handling and overall satisfaction compared to children wearing Proclear® 1 day single vision lenses. Children 11-15 years who were refit from single vision to MiSight 1 day also rated lenses highly and increased their contact lens wearing time.

How often do children wearing soft contact lenses experience adverse events?

This study examined rates of corneal infiltrative (or inflammatory) events, including microbial keratitis, in nine studies. Most study data was for children fitted at 12 years of age or younger and most wore daily disposables. Taking in data for almost 3,000 children and over 6,000 patient-years of wear, rates were found to be low, adding to the body of evidence that children appear to be safer soft contact lens wearers than adults.

How has Ireland embraced the use of myopia control contact lenses?

This retrospective study from Ireland found that despite recent increases in practitioners fitting myopia control contact lenses in Ireland, more than 60% of children were still managed with single vision correction only. Improving the prescribing rates of evidence-based myopia control treatments will ensure progressing myopes are less likely to miss appropriate intervention opportunities.

What is the risk-to-benefit balance for myopia control contact lenses in children?

This study found the risk of microbial keratitis for children fitted with contact lenses for myopia control was less than the risk of visual impairment from myopia progression to over 3D or axial lengths exceeding 26mm. If worn throughout childhood, the extra benefits of myopia control contact lenses outweigh the risks of infection, especially if the lenses are daily disposable.

How well does orthokeratology work over long periods of time?

This review investigated 18 years of practice data for the predictability, efficacy and safety of long-term ortho-k wear. The results showed that for at least one year’s wear, there was good efficacy and predictability of target refraction. Although corneal staining was common, serious adverse effects were found to be rare, particularly for children.

How does NaturalVue Multifocal 1 Day perform long-term for myopia?

This retrospective cohort analysis showed that NaturalVue Multifocal 1 Day contact lens wear appears to result in a mean refractive myopia progression of less than 0.25D per year, based on available data. Some limited axial length data was also presented.

A novel ring-focus soft contact lens design for myopia control

Two prototype myopia control soft contact lens designs with non-coaxial optics showed enhanced efficacy in one design and enhanced vision in the other, compared to dual-focus and single-vision designs. This initial data is for six months, and all myopia control contact lens designs showed close to 6/6 or 20/20 acuity equivalent.

How does the myopic peripheral retina respond to multifocal contact lens wear?

Analysis of the BLINK study results showed a global more than localized impact on slowing eye growth in +2.50 CD multifocal contact lens wear. The slowed growth effects were greater centrally than peripherally. This suggests local defocus responses may not provide the full story behind myopia control mechanisms.