Science

Science

Six year DIMS spectacle lens study shows continued efficacy and no rebound

The Defocus Incorporated Multiple Segments (DIMS) clinical study included a two year randomized controlled trial, which then extended to investigate continued efficacy over six years of wear, plus groups who switched from single vision to DIMS and back again. There was no evidence of a rebound effect. Visual acuity and binocular visual functions were similar across groups.

Can baseline axial length measurements be predictive of OrthoK efficacy?

This retrospective study assessed the relationship between baseline axial length and subsequent elongation for myopes wearing orthokeratology lenses. The results showed axial elongation was slower over two years for younger children with longer baseline axial lengths. This may help in approaches to optimizing myopia control.

Does ethnicity influence responses to myopia control treatment?

This editorial evaluated a range of single and multi-country clinical trials to examine the impact of race on treatment efficacy in myopia control. The authors found a similar slowing of axial elongation and myopia progression for East Asian and non-East Asian children across all studies.

Is an extra compression factor needed in orthokeratology for myopia control?

A new study has shown that an ‘extra compression factor’ of 1D, which is essentially increasing the treatment target, improved myopia control outcomes for children wearing orthokeratology. This would seem to indicate a different approach is needed for myopia control, but delving into the study reveals the story is not that simple.

Is red light therapy safe and effective for myopia control?

Repeated low-level red light (RLRL) therapy is showing impressive results for myopia control in children, with a two-year randomized controlled trial showing highly impressive results for slowing and even reversing axial elongation. While reported as safe, a new case report suggests otherwise. Read more about this red hot topic here.

Is the 20-20 rule effective advice in myopia management?

These two studies argue different sides of whether the 20/20 rule of regular breaks from near work can support myopia management, while also investigating other factors involved in digital eye strain such as dry eye symptoms and binocular vision function.

Johnson & Johnson Vision myopia research showcased at ARVO 2023

Johnson & Johnson Vision’s intent to lead with science was on full show at the recent ARVO at New Orleans. We look at 5 abstracts they presented, providing you summaries and the abstracts on topics such as efficacy in myopia control, myopia calculators and subjective vision outcomes for children and teens in soft contact lens designs for myopia.

Can we identify those likely to drop-out of orthokeratology?

This study found that over a 4-yr period, only 2% of children discontinued ortho-k wear, and the reasons were primarily due to adherence to lens wear schedules. This appears to be lower than in soft contact lenses. Encouraging children to continue wear as prescribed throughout the adaptation period, and to maintain compliance, should reduce likelihood of drop-out.

How satisfied are children wearing full-time daily disposable soft contact lenses?

Data from up to six years of wear in the landmark MiSight® 1 day clinical trial has shown similar outcomes for comfort, vision, handling and overall satisfaction compared to children wearing Proclear® 1 day single vision lenses. Children 11-15 years who were refit from single vision to MiSight 1 day also rated lenses highly and increased their contact lens wearing time.

How often do children wearing soft contact lenses experience adverse events?

This study examined rates of corneal infiltrative (or inflammatory) events, including microbial keratitis, in nine studies. Most study data was for children fitted at 12 years of age or younger and most wore daily disposables. Taking in data for almost 3,000 children and over 6,000 patient-years of wear, rates were found to be low, adding to the body of evidence that children appear to be safer soft contact lens wearers than adults.